Prof. Dr. İlknur EROL

She was born in Karabük in 1972. She completed her primary education at Karabük Demir Çelik Primary School, her secondary education at Karabük Beşbinevler Secondary School, and her high school education at Karabük Demir Çelik High School. She graduated from Marmara University Faculty of Medicine between 1989-1996. Between 1997-2002, she completed her specialization in the Department of Child Health and Diseases at Gazi University Faculty of Medicine.

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Tic disorder is one of the neurological conditions commonly seen in childhood and manifests itself with involuntary motor or vocal movements. It can usually be temporary, but in some children it may become permanent and negatively affect daily life and school performance.

The causes of tics in children are associated with genetic predisposition, stress factors, and imbalances in brain chemistry. A detailed history and neurological examination are important in diagnosis. When necessary, EEG and brain imaging methods contribute to the additional diagnostic process.

In the treatment approach, the priority is to evaluate to what extent the tics affect daily life. In mild tics, family support and psychoeducation may be sufficient, while in more advanced cases, medication treatment and behavioral therapies may be applied.

Family support is of great importance in tic disorder. Protecting the child’s self-confidence, providing correct information in the school environment, and reducing stress factors increase treatment success. With early diagnosis and appropriate intervention, children’s quality of life is improved.

CategoryInformation
Medical TermTic Disorders
Common NameTic, tic disorder
FrequencyTransient tics in 5–10% of school-age children; Tourette disorder at a rate of 0.1–1%
Age of OnsetUsually between ages 5–7; more common in boys
Main CausesGenetic predisposition, dopamine imbalances, stress, association with attention deficit/hyperactivity disorder (ADHD), learned behaviors
Types of TicsMotor Tics: Blinking, shrugging shoulders

Vocal Tics: Throat clearing, grunting

Simple Tics: Single muscle group

Complex Tics: Moving and involuntary sequences

Diagnostic MethodsClinical observation, family history, neurological examination, DSM-5 diagnostic criteria; EEG or neuropsychological tests if necessary, investigation of diseases caused by overactivity of the immune system
Types of DisordersTransient Tic Disorder, Chronic Tic Disorder, Tourette Syndrome
Characteristics of Tourette SyndromeBoth motor and vocal tics lasting longer than one year; shows fluctuation
Treatment MethodsFollow-up is sufficient in mild cases; behavioral therapy (habit reversal), psychoeducation; medication treatment in severe cases (antipsychotics, alpha agonists)
Conditions Requiring Emergency InterventionTics severely impairing the child’s functionality, self-harming behaviors
ComplicationsSocial adjustment problems, decline in school performance, lack of self-confidence, anxiety disorders
Follow-up and MonitoringFollow-up by Pediatric Neurology and psychiatrist, cooperation with behavior therapist, family education, immunomodulatory treatments in diseases caused by overactivity of the immune system, infection-preventive treatments
Lifestyle RecommendationsNo pressure should be placed on awareness of the tics, reducing stress, a structured daily routine, providing a positive social environment
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    What Is a Tic and How Does It Appear in Children?

    Tics are sudden, brief, and purposeless stereotyped movements (motor tics) or utterances (vocal tics). In children, tics can be seen in a wide range, from a simple blink to more noticeable motor movements such as shoulder shrugging and sniffing, or vocal expressions such as throat clearing, coughing, and grunting.

    In children, tics are like small “movements” or “sounds” that the body makes on its own. These are repetitive behaviors that occur suddenly, last a short time, and are outside the child’s control. You can think of it like a car headlight flashing on and off by itself; the child has difficulty controlling these movements. Tics are divided into two main categories: motor tics and vocal tics. Motor tics are body movements such as blinking, grimacing, and shoulder shrugging. Vocal tics are sounds such as throat clearing, coughing, and sniffing. Most of the time, motor tics appear before vocal tics, and simple tics may turn into more complex tics over time. For example, a tic that initially consists only of blinking may later include different motor movements such as grimacing and head shaking. The age of onset of tics in children is usually between 2 and 15 years, and they are most commonly seen at ages 6-7. During this period, head movements beginning in your child’s neck muscles and appearing as if they are throwing their hair away from their face may be one of the first signs. Over time, new tics may be added to these, and the head, eyes, or face are generally affected. Common motor tics include blinking, grimacing, lip smacking, and shoulder shrugging. Initial vocal tics are usually throat clearing, sniffing, or coughing. Children who especially make sniffing or coughing sounds may be unnecessarily treated under the assumption that they have allergies. Sounds such as grunting and hissing are other vocal tics. It should not be forgotten that these tics may increase during stressful times, decrease during moments of relaxation, and are generally not seen during sleep. In summary, tics are normal motor movements and sounds appearing in inappropriate settings and in an inappropriate manner.

    How Common Are Tic Disorders in Children and What Is Their Course?

    It can be said that tic disorders are quite common in childhood. While many children may experience transient tics at some point in their lives, some may have longer-lasting and more complex tic disorders.

    To understand how common tic disorders are in children, we can think of it like having the flu; many children get the flu at least once in their lives. Similarly, many children also experience transient tics at some point in their lives. Some studies show that about 20% of children experience tics at some point. However, most of these tics are transient and last less than a year. Transient tic disorder is the most common type of tic disorder. Longer-lasting tic disorders are less common. For example, Tourette Syndrome is a more complex condition in which both motor and vocal tics are seen together and may affect about 0.77% of children. Tic disorders are generally seen more often in boys than in girls. For Tourette Syndrome, this ratio is about 3:1. The severity of tics generally reaches its highest level between ages 8 and 12 and then tends to decrease during adolescence. In fact, most children are completely free of tics by the time they reach age 18. However, in a small minority, about 1%, tics may continue into adulthood. The course of tic disorders may vary from person to person. In some children, tics are mild and rare, while in others they may be more frequent and severe. The type and frequency of tics may change over time; while one tic disappears, a new one may appear in its place. This can be thought of like a child’s toys constantly changing.

    What Are the Causes of Tic Disorders in Children?

    Although the exact cause of tic disorders is not fully known, they are thought to arise as a result of a complex interaction of genetic, environmental, psychological, and immunological factors.

    While trying to understand the causes of tic disorders, we can imagine an orchestra. Just as many different instruments need to play in harmony for a musical work to emerge, many different factors also play a role in the emergence of tic disorders. Genetic factors form the foundation of this orchestra. The presence of individuals with tic disorder in the family increases the risk of tic development in the child. Studies especially conducted on identical twins show that genetic predisposition plays an important role in tic disorders. Certain areas in the brain, especially the basal ganglia and frontal cortex, play an important role in the control of movements. Dysfunction in these areas may contribute to the emergence of tics. Chemical messengers called neurotransmitters are also important in this process. Imbalances in neurotransmitters such as dopamine and serotonin may cause tics. Environmental factors may also play a role in the development of tics. Factors such as stress experienced by the mother during pregnancy, low birth weight, or birth complications may increase the child’s risk of developing tics. In addition, in some cases, immunological factors such as streptococcal infections are thought to cause the onset or worsening of tics. In this condition, called PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections), it is thought that antibodies produced by the body against streptococcal bacteria may affect certain areas of the brain, leading to tics and obsessive-compulsive behaviors. In recent years, it has been known that microbial infections other than streptococcal infections may also cause similar clinical pictures, and this condition is called PANS (Pediatric Acute-onset Neuropsychiatric Syndrome). Stimulant medications (used for attention deficit) may also trigger tics in genetically predisposed children. In summary, the cause of tic disorders is multifactorial and arises as a result of the complex interaction between genetic structure, brain functions, environmental factors, and the immune system.

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    How Are Tic Disorders Diagnosed in Children?

    The diagnosis of tic disorders in children is made primarily through careful taking of the medical history of the child and family and by observing the child. No specific laboratory test or imaging method can definitively diagnose tic disorders. First, the doctor conducts a detailed interview with the family to learn when the child’s tics started, what types of tics they have, how often they are seen, and how they have changed over time. The child’s medical history and whether there are tic disorders or similar conditions in the family are also important pieces of information. By observing the child at different times, the doctor evaluates the characteristics and frequency of the tics. Factors such as whether the tics increase in stressful situations or decrease during moments of relaxation are also taken into account in the diagnostic process. Internationally accepted diagnostic guidelines such as DSM-5 (Diagnostic and Statistical Manual of Mental Disorders, 5th Edition) and ICD-11 (International Classification of Diseases, 11th Revision) are used to classify tic disorders and determine the diagnostic criteria. These guidelines include certain criteria such as the duration of the tics, their type (motor or vocal), and age of onset. For example, for a diagnosis of transient tic disorder, the tics must have been present for less than one year, whereas for a diagnosis of Tourette Syndrome, both motor and vocal tics must have been present for at least one year and the onset must have been before age 18. The doctor also evaluates whether there are commonly accompanying conditions such as attention deficit hyperactivity disorder (ADHD) and obsessive-compulsive disorder (OCD) in addition to the tics. In some cases, especially in cases where the tics begin suddenly, throat culture or blood tests may be done to rule out streptococcal infection. EEG (electroencephalography) may be considered in cases where seizures are suspected. Ruling out other medical conditions that may cause tic-like movements (genetic diseases, medication side effects, etc.) is also an important part of the diagnostic process. Standard scales such as the Yale Global Tic Severity Scale (YGTSS) may also be used in the diagnostic process to assess the severity and frequency of the tics.

    What Other Conditions Commonly Accompany Tic Disorders?

    Tic disorders usually do not appear alone; just as a house has more than one room, a child with a tic disorder may also have other conditions at the same time. One of the most commonly accompanying conditions is attention deficit hyperactivity disorder (ADHD). Children with ADHD are generally hyperactive individuals with short attention spans, restlessness, difficulty concentrating, and difficulty controlling their impulses. Stimulant medications are used in the treatment of ADHD, but it should not be forgotten that these medications have the potential to increase tics in some genetically predisposed children. Another commonly seen condition is obsessive-compulsive disorder (OCD). Children with OCD may display ritualistic behaviors such as touching objects repeatedly, placing objects in a particular place, washing their hands repeatedly, or counting objects. These children generally have intrusive, distressing, and anxiety-provoking obsessive thoughts. In children, OCD may manifest itself in forms such as insisting that foods not touch each other, intolerance toward certain types of clothing (especially jeans), and not being able to wear lace-up shoes (because they become frustrated when they cannot tie the laces exactly equally). In addition, conditions such as PANDAS (pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection) that may occur after streptococcal infection, and PANS (Pediatric Acute-onset Neuropsychiatric Syndrome) that may be seen after similar microbial infections, may also accompany tic disorders. In these conditions, preventive treatments against infection and immune-regulating treatments may be applied. Anxiety disorders, learning difficulties, and sleep problems may also be seen more frequently in children with tic disorders. Therefore, the evaluation of a child with a tic disorder should not focus only on the tics, but should also take a comprehensive approach by considering other accompanying conditions.

    What Are the Treatment Methods for Tic Disorders in Children?

    The treatment of tic disorders in children is planned individually according to the severity of the tics, the child’s age, the presence of other accompanying conditions, and the effect on the child’s quality of life. The main goal of treatment is to reduce the frequency and severity of the tics, support the child’s social and emotional well-being, and treat accompanying conditions.

    We can compare the methods used in the treatment of tic disorders to arranging a garden. Just as clearing the weeds in a garden and ensuring that the flowers grow healthily, both behavioral and medication treatments may be used in the treatment of tic disorders. Behavioral treatments, especially CBIT (Comprehensive Behavioral Intervention for Tics) and HRT (Habit Reversal Therapy), are accepted as first-line treatment in the management of tics. HRT teaches the child to recognize the urge felt before the tic and to develop an alternative behavior that will counter this urge. CBIT, on the other hand, is a more comprehensive approach that also includes HRT and contains psychoeducation about tics, functional analysis aimed at understanding the triggers and consequences of tics, and relaxation techniques that help manage stress. Medication treatments are generally considered when tics are more severe or when behavioral treatments are insufficient. Medications used may include alpha-2 adrenergic agonists (guanfacine, clonidine), antipsychotics (risperidone, aripiprazole), and in some cases topiramate and botulinum toxin injections. While alpha-2 adrenergic agonists may be particularly useful in situations accompanied by ADHD, antipsychotics are more effective in reducing the frequency and severity of tics. However, since these medications may have some side effects, it is important that they are used carefully and under a doctor’s supervision. In recent years, studies are also continuing on new medications such as valbenazine and ecopipam. During the treatment process, it is also important to provide detailed information to the child and family about tic disorder, direct them to support groups, and cooperate with the school. In addition, appropriate treatment of accompanying conditions such as ADHD and OCD may significantly improve the child’s general well-being. It should not be forgotten that the treatment of tic disorders is a process that requires patience and care, and each child’s response to treatment may be different.

    How Can Children with Tic Disorders and Their Families Be Supported?

    Supporting a child with tic disorder is like growing a sapling; it requires patience, understanding, and proper care. First of all, it is important to remember that your child’s tics are not under their control and that this condition may also be challenging for them. Never criticize, judge, or punish your child because of their tics. Instead, adopt an understanding and supportive attitude toward them. As a family, having accurate and up-to-date information about tic disorder will help you cope better with this condition. Obtain information from your doctor and reliable sources. By informing the teachers and other authorities at your child’s school about tic disorder, you can also contribute to the creation of a supportive atmosphere in the school environment. It should be remembered that stress may increase tics. For this reason, try to create a calm and peaceful environment for your child at home and at school. Adequate sleep, regular nutrition, and physical activity also play an important role in the management of tics. Create opportunities for your child to participate in activities related to their interests, strengthen social relationships, and increase self-confidence. Joining support groups where you can meet other children with tic disorder and their families may be beneficial for both you and your child. In these groups, you can share your experiences, exchange information, and support one another. Try to understand your child’s emotional needs and do not hesitate to seek support from a child psychologist or psychiatrist if necessary.

    An increased immune response to infections caused by the bacteria called beta-hemolytic streptococcus, which causes tonsil infections in children, may also lead to a condition called PANDAS characterized by tics and anxiety disorder. In these patients, treatments that prevent encountering this microbe and sometimes treatments that reduce increased immunity may be beneficial.

    Frequently Asked Questions

    What are the biological and environmental factors underlying the development of tic disorder in children?

    Genetic predisposition, imbalances in brain chemistry, overactivity of the immune system, and stressful environmental events play an important role in the emergence of tic disorders. Family history of tics and anxiety may also increase the risk.

    Which risk groups are more affected among children with tic disorder?

    Tic disorder is observed more frequently and more severely in children with additional psychiatric problems such as attention deficit and hyperactivity disorder and obsessive-compulsive disorder. It is also more common in boys.

    What daily habits or lifestyle factors trigger tic disorder in children?

    Factors such as intense screen exposure, insufficient sleep, excessive caffeine consumption, and school stress may increase the frequency and severity of tics. Routine and healthy habits may reduce the risk.

    When is early intervention necessary for tic disorder in children?

    If tics significantly affect daily life, school performance, or social relationships, or if they are gradually increasing, early intervention is important. Early support may prevent long-term problems.

    What are the complications that may develop later in tic disorder in children?

    Untreated tics may lead to emotional problems such as social isolation, loss of self-confidence, and anxiety. School performance and peer relationships may also be negatively affected.

    Which methods are preferred in the treatment of tic disorder in children?

    Behavioral therapies, especially habit reversal training (CBIT), are the first choice in tic disorder. In severe cases, medication treatment may be added and family education is supported. In diseases such as PANS and PANDAS, characterized by an excessive immune response to infections, immunomodulatory treatments and protective antibiotics against infection may be used.

    What difficulties may children with tic disorder face in school and social life?

    Because of tics, children may be misunderstood by friends, become the subject of ridicule, and experience concentration problems at school. A supportive environment is of great importance.

    How should families of children with tic disorder be supported?

    Families should know that tics are involuntary and should behave patiently. They are recommended to access informative resources and receive psychological counseling when necessary.

    What is the recovery period and outcome of tic disorder in children?

    In many children, tics may decrease over time or disappear completely. However, in some cases they may be permanent, so follow-up and treatment when necessary are important.

    How are the psychological and emotional effects of tic disorder in children managed?

    The child’s self-confidence should be supported, stress-reducing methods should be taught, and psychotherapy should be applied if necessary. The family’s attitude is also effective in the recovery process.

    Which Department or Doctor Should Be Consulted for Tic Disorder in Children?

    Tic disorder in children may be seen in the form of involuntary and repetitive motor movements or vocalizations. The Pediatric Neurology department should be consulted to determine whether this condition is of neurological origin and for treatment planning.